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Search Results to Charles A Dinarello

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Item TypeName
Academic Article Fever, interleukin-1 and host defense against malignancy.
Academic Article The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
Academic Article Human leukocytic pyrogen test for detection of pyrogenic material in growth hormone produced by recombinant Escherichia coli.
Academic Article Production of fever and its effects on the host.
Academic Article Molecular basis of fever in humans.
Academic Article Coagulation of whole blood stimulates interleukin-1 beta gene expression.
Academic Article Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
Academic Article Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones.
Academic Article Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.
Academic Article Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera.
Academic Article Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro.
Academic Article Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
Academic Article IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.
Academic Article Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays.
Academic Article Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Dissociation of transcription from translation of human IL-1 beta: induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event.
Academic Article Osmotic regulation of cytokine synthesis in vitro.
Academic Article Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production.
Academic Article Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Academic Article Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro.
Academic Article Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5-lipoxygenase inhibitor.
Academic Article Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro.
Academic Article Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria.
Academic Article p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function.
Academic Article The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo.
Academic Article Immunoregulatory functions of paf-acether. IV. Enhancement of IL-1 production by muramyl dipeptide-stimulated monocytes.
Academic Article Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2.
Academic Article The pyrogenicity of the synthetic adjuvant muramyl dipeptide and two structural analogues.
Academic Article Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF.
Academic Article Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.
Academic Article Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
Academic Article The in vivo and in vitro effects of interleukin-1 and tumor necrosis factor on murine cytomegalovirus infection.
Academic Article The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ? cells in vivo and in vitro.
Academic Article A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone.
Academic Article ?2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo.
Academic Article Enhancement of in-vitro human interleukin-1 production by sodium acetate.
Academic Article Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans.
Academic Article Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon.
Academic Article Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate.
Academic Article Detection of endotoxin-like interleukin-1-inducing activity during in vitro dialysis.
Academic Article Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin.
Academic Article Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro.
Academic Article C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha.
Academic Article Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
Academic Article The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor.
Academic Article Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans.
Academic Article Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.
Academic Article Stimulatory effect of interleukin-1 upon hepatic metabolism.
Academic Article In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1.
Academic Article Prostaglandin formation in feline cerebral microvessels: effect of endotoxin and interleukin-1.
Academic Article Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans.
Academic Article The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies.
Academic Article Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist.
Academic Article Production of leukocytic pyrogen from phagocytes of neonates.
Academic Article Comparison of first use and reuse of cuprophan membranes on interleukin-1 receptor antagonist and interleukin-1 beta production by blood mononuclear cells.
Academic Article Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress.
Academic Article Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood.
Academic Article Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression.
Academic Article In vitro production of interleukin-1 receptor antagonist in chronic renal failure, CAPD and HD.
Academic Article Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
Academic Article Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning.
Academic Article Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
Academic Article Histone hyperacetylation is associated with amelioration of experimental colitis in mice.
Academic Article Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1 beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth.
Academic Article Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy.
Academic Article Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Differences in signaling pathways by IL-1beta and IL-18.
Academic Article Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.
Academic Article Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement.
Academic Article Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor.
Academic Article Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas.
Academic Article Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Academic Article The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.
Academic Article Interleukin-1 beta in human colostrum.
Academic Article Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation.
Academic Article Induction of interleukin-1 and tumor necrosis factor during in vitro hemodialysis with different membranes.
Academic Article Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells.
Academic Article Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis.
Academic Article Interaction of IL 1 and TPA in modulation of eosinophil function.
Academic Article Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity.
Academic Article Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium.
Academic Article A radioimmunoassay for human interleukin-1 alpha: measurement of IL-1 alpha produced in vitro by human blood mononuclear cells stimulated with endotoxin.
Academic Article Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
Academic Article Human interleukin-1 production during hemodialysis.
Academic Article Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.
Academic Article Parasite-monocyte interactions in human leishmaniasis: production of interleukin-1 in vitro.
Academic Article Cellular interactions in the generation and expression of histamine-induced suppressor activity.
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
Grant Pathogenesis of Fever in Man
Concept In Vitro Techniques
Academic Article Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.

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